Genotoxicity in the absence of inflammation after tungsten inhalation in mice [Epub ahead of print]
Tidsskriftartikel
1,3-butadiene: Scientific basis for setting a health-based occupational exposure limit
Rapport
Polycyclic aromatic hydrocarbons containing benzo[a]pyrene: Scientific basis for setting a health-based occupational exposure limit (Polycycliske aromatiske hydrocarboner indeholdende benzo[a]pyren: Videnskabelig dokumentation for helbredsbaserede risikoestimater)
Distribution, metabolism, excretion, and toxicity of implanted silver: A review
Development of a standard operating procedure for the DCFH-DA acellular assessment of reactive oxygen species produced by nanomaterials
Safe(r) by design guidelines for the nanotechnology industry
Report of the 1st and 2nd mystery of reactive oxygen species conferences
Leder
Grouping MWCNTs based on their similar potential to cause pulmonary hazard after inhalation: A case-study
Reactive oxygen species in the adverse outcome pathway framework: Toward creation of harmonized consensus key events
Assessment of primary and inflammation-driven genotoxicity of carbon black nanoparticles in vitro and in vivo
Systematic review on primary and secondary genotoxicity of carbon black nanoparticles in mammalian cells and animals
Assessing the transferability and reproducibility of 3D in vitro liver models from primary human multi-cellular microtissues to cell-line based HepG2 spheroids
Ny dokumentation for helbredsbaserede grænseværdier i arbejdsmiljøet for 10 stoffer
Predicting nanomaterials pulmonary toxicity in animals by cell culture models: Achievements and perspectives
Unchanged pulmonary toxicity of ZnO nanoparticles formulated in a liquid matrix for glass coating [Epub ahead of print]
Indoor PM2.5 from occupied residences in Sweden caused higher inflammation in mice compared to outdoor PM2.5
A review of the current state of nanomedicines for targeting and treatment of cancers: achievements and future challenges
Pulmonary toxicity of synthetic amorphous silica – effects of porosity and copper oxide doping
A transcriptomic overview of lung and liver changes one day after pulmonary exposure to graphene and graphene oxide
Zinc oxide: Scientific basis for setting a health-based occupational exposure limit
Accelerated atherosclerosis caused by serum amyloid A response in lungs of ApoE mice
Respirable quartz and other crystalline silica polymorphs: Scientific basis for setting a health-based occupational exposure limit
An integrated approach to testing and assessment of high aspect ratio nanomaterials and its application for grouping based on a common mesothelioma hazard
Reactive oxygen species production, genotoxicity and telomere length in FE1-Muta™Mouse lung epithelial cells exposed to carbon nanotubes
Towards FAIR nanosafety data
Inflammatory response, reactive oxygen species production and DNA damage in mice after intrapleural exposure to carbon nanotubes
Integrative approach in a safe by design context combining risk, life cycle and socio-economic assessment for safer and sustainable nanomaterials
In vitro-in vivo correlations of pulmonary inflammogenicity and genotoxicity of MWCNT
Genotoxicity of multi-walled carbon nanotube reference materials in mammalian cells and animals
Pro-inflammatory response and genotoxicity caused by clay and graphene nanomaterials in A549 and THP-1 cells
Acute hazard assessment of silver nanoparticles following intratracheal instillation, oral and intravenous injection exposures
Effects of physicochemical properties of TiO nanomaterials for pulmonary inflammation, acute phase response and alveolar proteinosis in intratracheally exposed mice
Pulmonary toxicity of Fe2O3, ZnFe2O4, NiFe2O4 and NiZnFe4O8 nanomaterials: Inflammation and DNA strand breaks
Acute phase response as a biological mechanism-of-action of (nano)particle-Induced cardiovascular disease
Pulmonary toxicity of silver vapours, nanoparticles and fine dusts: A Review
Effect of renewable fuels and intake O2 concentration on diesel engine emission characteristics and Reactive Oxygen Species (ROS) formation
Organomodified nanoclays induce less inflammation, acute phase response, and genotoxicity than pristine nanoclays in mice lungs
Particle characterization and toxicity in C57BL/6 mice following instillation of five different diesel exhaust particles designed to differ in physicochemical properties
Safe(r) by design implementation in the nanotechnology industry
Pulmonary toxicity of two different multi-walled carbon nanotubes in rat: Comparison between intratracheal instillation and inhalation exposure
Kulstofnanorørs fysisk-kemiske egenskaber forudsiger langvarig inflammation på mus
Nanomaterial grouping: Existing approaches and future recommendations
Acute phase response and inflammation following pulmonary exposure to low doses of zinc oxide nanoparticles in mice
Chromium (VI) compounds: Assessment of SCOEL/REC/386
Asbestos: Scientific basis for setting a health-based occupational exposure limit
Fra forskning i nanomaterialer til forebyggelse på arbejdspladser
Commentary: The chronic inhalation study in rats for assessing lung cancer risk may be better than its reputation
Kommentar/debat
Primary genotoxicity in the liver following pulmonary exposure to carbon black nanoparticles in mice
Toxicity of pristine and paint-embedded TiO nanomaterials
Corrigendum to "MWCNTs of different physicochemical properties cause similar inflammatory responses, but differences in transcriptional and histological markers of fibrosis in mouse lungs" [Toxicol. Appl. Pharmacol., 284 (2015) 16-32]
Insights into possibilities for grouping and read-across for nanomaterials in EU chemicals legislation
Physicochemical predictors of multi-walled carbon nanotube-induced pulmonary histopathology and toxicity one year after pulmonary deposition of 11 different multi-walled carbon nanotubes in mice
Radicals generated by nanoparticles in contact with liquid water using spin trapping and mass spectrometry
Konferenceabstrakt til konference
Poster
Diesel exhaust particles: Scientific basis for setting a health-based occupational limit
Carbon nanotubes: Scientific basis for setting a health-based occupational exposure limit
Carbon black nanomaterials: Scientific basis for setting a health-based occupational exposure limit
Titanium dioxide nanomaterials: Scientific basis for setting a health-based occupational exposure limit
Impact of serum as a dispersion agent for in vitro and in vivo toxicological assessments of TiO nanoparticles
Surface modification does not influence the genotoxic and inflammatory effects of TiO2 nanoparticles after pulmonary exposure by instillation in mice
Biodistribution of carbon nanotubes in animal models
Identification of gene transcription start sites and enhancers responding to pulmonary carbon nanotube exposure in vivo
Hepatic hazard assessment of silver nanoparticle exposure in healthy and chronically alcohol fed mice
Differences in inflammation and acute phase response but similar genotoxicity in mice following pulmonary exposure to graphene oxide and reduced graphene oxide
Challenges on the toxicological predictions of engineered nanoparticles
Weight of evidence analysis for assessing the genotoxic potential of carbon nanotubes
Multi-walled carbon nanotube-induced genotoxic, inflammatory and pro-fibrotic responses in mice
Grouping of manufactured nanomaterials: Strategies within NANoREG and NanoReg2
Morphological changes in mouse liver one year after intratracheal instillation to carbon nanotubes
Radicals generated by nanomaterials in contact with liquid water using spin trapping and mass spectrometry
Readiness of control banding tools for safe innovation and regulatory occupational exposure assessment of nanomaterials
Risk assessment analysis on candidate nanomaterials at different stages of the innovation change prior to Safe by Design-implementation. First results from Nanoeg2 H2020 project (WP2)
Hepatic toxicity assessment of cationic liposome exposure in healthy and chronic alcohol fed mice
Influence of dispersion medium on nanomaterial-induced pulmonary inflammation and DNA strand breaks: investigation of carbon black, carbon nanotubes and three titanium dioxide nanoparticles
Developmental toxicity of engineered nanomaterials
Bidrag til bog/antologi
Monocyte adhesion induced by multi-walled carbon nanotubes and palmitic acid in endothelial cells and alveolar-endothelial co-cultures
Kulstofnanorør påvirker lunger og blodbaner
Atherosclerosis and vasomotor dysfunction in arteries of animals after exposure to combustion-derived particulate matter or nanomaterials
A multilaboratory toxicological assessment of a panel of 10 engineered nanomaterials to human health-ENPRA Project - The highlights, limitations, and current and future challenges
No cytotoxicity or genotoxicity of graphene and graphene oxide in murine lung epithelial FE1 cells in vitro
Epoxy composite dusts with and without carbon nanotubes cause similar pulmonary responses, but differences in liver histology in mice following pulmonary deposition
Inflammation and vascular effects after repeated intratracheal instillations of carbon black and lipopolysaccharide
Åreforkalkning og funktionsforstyeelse af arterier efter udsættelse for forbrændingspartikler og nanopartikler
Cardiovascular health effects of oral and pulmonary exposure to multi-walled carbon nanotubes in ApoE-deficient mice
DNA damage following pulmonary exposure by instillation to low doses of carbon black (Printex 90) nanoparticles in mice
Measurement of oxidative damage to DNA in nanomaterial exposed cells and animals
MWCNTs of different physicochemical properties causes similar inflammatory responses, but differences in transcriptional and histological markers of fibrosis in mouse lungs
Transcriptional profiling identifies physicochemical properties of nanomaterials that are determinants of the in vivo pulmonary response
Time-dependent subcellular distribution and effects of carbon nanotubes in lungs of mice
Changes in cholesterol homeostasis and acute phase response link pulmonary exposure to multi-walled carbon nanotubes to risk of cardiovascular disease
DNA strand breaks, acute phase response and inflammation following pulmonary exposure by instillation to the diesel exhaust particle NIST1650b in mice
Comparative hazard identification by a single dose lung exposure of zinc oxide and silver nanomaterials in mice
Carbon black nanoparticles and other problematic constituents of black ink and their potential to harm tattooed humans
Intratracheally instilled titanium dioxide nanoparticles translocate to heart and liver and activate complement cascade in the heart of C57BL/6 mice
Acute and subacute pulmonary toxicity and mortality in mice after intratracheal instillation of ZnO nanoparticles in three laboratories
Kroppens reaktion på lungeeksponering for forskellige typer af kulstofnanorør - et studie i mus
Carbon black nanoparticles induce biphasic gene expression changes associated with inflammatory responses in the lungs of C57BL/6 mice following a single intratracheal instillation
Carbon nanotubes. Types, products, market, and provisional assessment of the associated risks to man and the environment
Indånding af nanomaterialer øger risikoen for hjertekarsygdom
FIB-SEM imaging of carbon nanotubes in mouse lung tissue
Vascular effects of multiwalled carbon nanotubes in dyslipidemic ApoE-/- mice and cultured endothelial cells
Particle-induced pulmonary acute phase response may be the causal link between particle inhalation and cardiovascular disease
Role of oxidative stress in carbon nanotube-generated health effects
Tissue distribution and elimination after oral and intravenous administration of different titanium dioxide nanoparticles in rats
Nanoparticles, carbon nanotubes and risk for lung cancer
Engineered nanomaterial risk. Lessons learnt from completed nanotoxicology studies: potential solutions to current and future challenges
Pulmonary instillation of low doses of titanium dioxide nanoparticles in mice leads to particle retention and gene expression changes in the absence of inflammation
Øger indånding af (nano)partikler risikoen for hjerte-kar-sygdom?
Black tattoo inks induce reactive oxygen species production correlating with aggregation of pigment nanoparticles and product brand but not with the polycyclic aromatic hydrocarbon content
Particle-induced pulmonary acute phase response correlates with neutrophil influx linking inhaled particles and cardiovascular risk
Bioaccumulation and ecotoxicity of carbon nanotubes
Validation of freezing tissues and cells for analysis of DNA strand break levels by comet assay
Transcriptomic analysis reveals novel mechanistic insight into murine biological responses to multi-walled carbon nanotubes in lungs and cultured lung epithelial cells
Carbon black nanoparticle intratracheal instillation does not alter cardiac gene expression
Akutfaserespons i lungerne - en mulig mekanisk forklaring på partikelforårsaget hjerte-kar-sygdom
Inflammatory and genotoxic effects of nanoparticles designed for inclusion in paints and lacquers
Pulmonary exposure to carbon black by inhalation or instillation in pregnant mice: Effects on liver DNA strand breaks in dams and offspring
Inflammatory and genotoxic effects of sanding dust generated from nanoparticle-containing paints and laquers
Carbon black nanoparticle instillation induces sustained inflammation and genotoxicity in mouse lung and liver
Nanotitanium dioxide toxicity in mouse lung is reduced in sanding dust from paint
"NANOKEM" - nanopartikler i farve og lakindustrien - eksponering og toksiske effekter
Hepatic and pulmonary toxicogenomic profiles in mice intratracheally instilled with carbon black nanoparticles reveal pulmonary inflammation, acute phase response, and alterations in lipid homeostasis
Carbon black nanoparticle intratracheal installation results in large and sustained changes in the expression of miR-135b in mouse lung
Mutationsspektrum: Mod en bedre forståelse af Printex 90 genotoksiske virkningsmekanismer
Mutation spectrum in FE1-mutaTM mouse lung epithelial cells exposed to nanoparticulate carbon black
Nanopartikler i arbejdsmiljøet - stor ståhej for ingenting eller tid til rettidig omhu?
Mutagenicity of carbon nanomaterials
Modest effect on plaque progression and vasodilatory function in atherosclerosis-prone mice exposed to nanosized TiO2
Genotoxicity of nanoparticles in vivo
Deliverable 2: Standard operating procedures for characterization of the selected manufactured nanomaterials types
Deliverable 3: Final protocol for producing suitable manufactured NM exposure media
Role of oxidative damage in toxicity of particulates
Genotoxicity of unmodified and organo-modified montmorillonite
Oxidative stress, inflammation and DNA damage in rats after intratracheal instillation or oral exposure to ambient air and wood smoke particulate matter
Pulmonary exposure to carbon black nanoparticles and vascular effects
Preliminary risk evaluation of nano-(organo)-clay powders in the production of polymer nanocomposites. Part of nanoplast
In vitro and in vivo toxicity of nanoclays [organo-modified montmorillonite)
Lung inflammation and genotoxicity following pulmonary exposure to nanoparticles in ApoE-/- mice
Oxidatively damaged DNA in rats exposed by oral gavage to C60 fullerenes and single-walled carbon nanotubes
Modest vasomotor dysfunction induced by low doses of C60 fullerenes in apolipoprotein E knockout mice with different degree of atherosclerosis
Små rør med store muligheder
Investigation of release of QACs from nanoclays using in vitro extraction and LC-MS/MS
Investigation of release of QACs from nanoclays using ASE extraction and LC-MS/MS
Biodistribution of gold nanoparticles in mouse lung following intratracheal instillation
Toxicity of carbon nanotubes: Research at the National Research Centre for the Working Environment
In vitro toxicity of carbon nanotubes and naoclays )organoclays) used in plastic composite materials
Safety of carbon nanotubes: A Danish Perspective
Genotoxicity, cytotoxicity and reactive oxygen species induced by single-walled carbon nanotubes and C60 fullerenes in the FE1-MutaTMMouse lung epithelial cells
Diesel exhaust particles are mutagenic in FE1-MutaTM mouse lung epithelial cells
Hazard assessment of engineered nanoparticles
Mutagenicity, genotoxicity and inflammation caused by nanoparticles
Ph.d.-afhandling
Nanotoxicology and nanosafety
Risk assessment of engineered nanoparticles: The particle risk project
Genotoxicity, inflammation and physico-chemical properties of fine particle samples from an incineration energy plant and urban air
Increased mutant frequency by carbon black, but not quartz, in the lacZ and cII transgenes of muta(trade mark)mouse lung epithelial cells
Carbon nanoparticle-induced formation of reactive oxygen species
Detection and quantification of reactive oxygen species generated in nanoparticle aqueous suspensions and in human lung cell exposures
Cytokine expression in mice exposed to diesel exhaust particles by inhalation. Role of tumor necrosis factor
Two regions in chromosome 19q13.2-3 are associated with risk of lung cancer
XRCC3 polymorphisms and risk of lung cancer
No association between OGGI Ser326Cys polymorphism and breast cancer risk
No association between the DNA repair gene XRCC3 T241M polymorphism and risk of skin cancer and breast cancer
Genetiske variationer i gener, der er involveret i oxidativt stress som risikofaktor for brystkræft
Multiple single nucleotide polymorphisms on human chromosome 19q13.2-3 associate with risk of basal cell carcinoma
Association of chromosome 19q13.2-3 haplotypes with basal cell carcinoma: tentative delineation of an involved region using data for single nucleotide polymorphisms in two cohorts
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